ABOUT (+)-JQ-1 MECHANISM OF ACTION

Indeed, TERT phosphorylation has been revealed for being needed for telomerase activation. b Effect of BETi on telomere regulation. BETi contend with acetylated histones for the binding for the BRD4 bromodomains releasing BRD4 from limited telomere, destabilizing telomere safety elaborate Firm and lowering Telomerase activity. The progressive short